According to statistics, every 1% reduction in a drug's moisture content can increase its stability by approximately 5%. Freeze Dryer play a crucial role in this process. By employing freeze-drying technology, these machines not only preserve the active ingredients of pharmaceuticals but also significantly enhance their long-term storage capabilities.
Take a biopharmaceutical company in Jiangsu as an example. By precisely controlling the pre-freezing rate of the "BOTH" freeze dryer, protein-based drugs can form fine, uniform ice crystal structures at -40°C. Compared to traditional slow freezing, the structural integrity of the drugs improved by 20%. This optimization directly reduced the loss of activity during the subsequent drying process due to structural damage, resulting in a 15% improvement in stability.
During the sublimation drying stage, the intelligent control system of the freeze dryer plays a key role. A pharmaceutical company in Henan utilized the advanced PID controller of the "BOTH" freeze dryer to dynamically adjust the vacuum level, ensuring that moisture sublimated quickly and evenly while preventing the degradation of heat-sensitive components. Data shows that the residual moisture of the drugs was reduced to below 2%, and stability increased by 25%.
The re-drying step of the freeze dryer further reduces the drug’s moisture content, while the integrated sterile packaging system provides the final line of defense for pharmaceutical stability. A company in Rizhao achieved seamless integration of freeze drying with sterile filling lines, ensuring a completely sterile process from drying to packaging. This resulted in a final moisture content of less than 1%, enhancing stability by 30%. The optimization of this entire process not only increases the product's market competitiveness but also ensures the safe use of medicine for patients.
In recent years, continuous innovations in freeze-dryer technology have emerged, such as using low-temperature plasma surface treatment to reduce drug adsorption and introducing continuous freeze-drying systems to improve production efficiency. These technological advancements have not only led to a qualitative leap in drug stability but have also greatly promoted the modernization of the pharmaceutical industry.
Freeze dryers are undoubtedly a wise choice for safeguarding pharmaceutical stability. With precise control in the pre-freezing, sublimation drying, re-drying, and sterile packaging processes, they provide a solid barrier for the stability of pharmaceuticals. Behind each successful case and data point is a strong testament to the ongoing breakthroughs and innovations in freeze-drying technology. In today’s pursuit of higher-quality medical products, the "BOTH" freeze dryer is undoubtedly a smart choice for pharmaceutical companies to improve drug stability and ensure patient safety.
If you are interested in our Freeze Dryer or have any questions, please feel free to contact us. As a professional manufacturer of freeze dryers, we offer a wide range of specifications including home, laboratory, pilot and production models. Whether you need household equipment or large industrial equipment, we can provide you with the best quality products and services.
Post time: Nov-11-2024
